DIABETIC PATIENTS ON DIALYSIS SHOULD BE TRANSPLANTED

Abstract

P315 Body: Diabetes Mellitus (DM) is the most common cause of end-stage renal disease (ESRD). The mortality and morbidity of DM patients on dialysis is high, with survival rate 61% at 2 yrs. and 26% at 5 yrs. For diabetic patients with ESRD, several recent studies have shown transplantation is better than dialysis. Aim of Study: 1). To compare the renal transplant outcome between diabetic vs. non-diabetic patients, and 2) to compare mortality rate of diabetic patients remaining on dialysis vs. those transplanted. Methods: Retrospectively we analysed 336 diabetic patients waiting for transplant vs. 453 diabetic patients who received a kidney transplant. Graft and patient survival of diabetic transplanted patients (n=453) compared to non-diabetic patients (n=1150) transplanted between 1996 to 2002. Anova T-test and Kaplan Meier were used for data analyses. Results:FigureFigureConclusion: Despite additional risk factors associated with transplantation for diabetic patients, the mortality rate of diabetic patients remaining on dialysis is significantly greater than those transplanted at 20% vs. 8% (P=0.001). However, the post-transplant patient and graft survival of diabetic vs. non-diabetic patients is equivalent. In conclusion, transplantation is the best option for diabetic patients with ESRD.