Abstract
When last commented on in theArchivestwo years ago, 1 the diabetic renal-retinal syndrome was viewed as a usually serious and often devastating complication of long-standing diabetes for which near-term improvement in prognosis was likely. At that time, it was noted that about half of insulindependent diabetics experience renal failure in a mean of 20 years. Survival of treated uremic diabetics was dismal, with only one in five patients surviving beyond two years of peritoneal dialysis and about one in two living longer than three years after a cadaveric kidney transplant or when sustained by hemodialysis. Interest in diabetic nephropathy since then has been intensified by numerous articles indicating that glomerulosclerosis, the major renal pathological finding in protracted diabetes, is a consequence of hyperglycemia per se. Evidence supporting this contention is drawn from two sources—animal models of diabetes and the fate of renal allografts from nondiabetic donors to diabetic
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
