Abstract
Background and Purpose: Diabetes and ischemic stroke are common diseases that frequently occurring together. Several studies have shown that people with diabetes have approximately twice the risk of ischemic stroke compared with those without diabetes. Although diabetes is a strong risk factor for ischemic stroke, it is still unclear whether risk factors, neuroimaging findings and hospital outcome are different in diabetic and nondiabetic patients. The aim of the present study was to evaluate cerebrovascular risk factor prevalence, neuroimaging findings and hospital outcome in patients between diabetic and non-diabetic of ischaemic stroke.Methods: We conducted a prospective study of 380 consecutive patients with cerebral infarction admitted into Rangpur Medical College Hospital over a 18-month period. With the use of a simple identical data sheet, we recorded the demographics, cardiovascular risk factors, neuroimaging findings and outcome in ischemic stroke patients with and without diabetes.Results: Overall, diabetes was present in 76 patients (20%). Diabetic patients, compared with those without diabetes, were younger (p=.034) and they were more likely to have hypertension (69.7%), hyperlipidemia (28.9%), ischemic heart disease (22.4%), previous cerebral infract (23.7%) and renal impairment (19.7%). Diabetic infract more frequently occurred in thalamus (11.8%), pons (9.2%) and with cerebral posterior involvement (13.2%). Mortality was higher in diabetic group (P = .046).Conclusions: Diabetic patients had higher risk burden for ischemic stroke with poorer short term hospital outcome than non-diabetic subjects. So control of diabetes and other risk factors along with a strict observation of adult individuals healthy life-style should warrant successful ischemic stroke prevention in our country.J MEDICINE July 2017; 18 (2) : 75-79
Highlights
Stroke and diabetes mellitus (DM) are two of the leading causes of death worldwide
Materials and Methods: Study population: This study was performed among the patients admitted into Department of Medicine, Rangpur medical college hospital, Rangpur from January 2010 to June 2011 with the clinical features and CT scan findings of stroke. 380 patients with cerebral infarction was selected by purposive sampling
This may be explained by a stronger disposition to stroke in the diabetic patient, because diabetes mellitus is associated with accelerated atherogenesis and due to the fact that diabetic stroke patients have more often other cerebrovascular risk factors as, in our study, hypertension, hyperlipidemia and ischemic heart disease, previous cerebral infarction which in turn were independent predictors of ischemic stroke in the diabetic population as previously reported by others .17,21
Summary
The prevalence of stroke in adult patients with DM is high and the risk of death is about twice that of people of similar age without DM.[1] In the largest case control study with adjustment for multiple known risk factors,[2] the risk of stroke for diabetic individuals increased by 2.3. Several studies have shown that people with diabetes have approximately twice the risk of ischemic stroke compared with those without diabetes. diabetes is a strong risk factor for ischemic stroke, it is still unclear whether risk factors, neuroimaging findings and hospital outcome are different in diabetic and nondiabetic patients.The aim of the present study was to evaluate cerebrovascular risk factor prevalence, neuroimaging findings and hospital outcome in patients between diabetic and non-diabetic of ischaemic stroke
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