Abstract
An association of plasma epoxylipids, epoxyeicosatrienoic acids (EETs), and their corresponding diols, dihydroxyeicosatrienoic acids (DHETs), with diabetes risk in American Indians was identified by Lemaitre et al. in this edition of EBioMedicine [1]. The findings of this prospective study on plasma samples from the Strong Heart Study found a novel association of high total plasma 14,15-DHET levels with lower plasma insulin and lower glucose levels. On the other hand, the study failed to find an association for total plasma EETs and DHETs and diabetes risk among American Indians.
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