Abstract
Glucose intolerance was found in four adult chimpanzees. The response of glucose, insulin, C-peptide, and glucagon to intravenous glucose and tolbutamide stimulations revealed impaired glucose clearance, deficient pancreatic secretion of insulin and C-peptide, and elevated glucagon levels. Pancreatic islets in a diabetic chimpanzee were hypercellular, possible due to alpha-cells. Minimal or no insulin was observed in beta-cells. Results are consistent with the occurrence of noninsulin-dependent diabetes mellitus, which may be more prevalent in chimpanzees than heretofore suspected.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
