Diabetes mellitus effect on patients with myocardial infarction through some biochemical markers with magnesium and vitamin D in Basrah

Abstract

Cardiovascular diseases, including coronary artery disease (CAD) are a serious health threat (Curtis et al, 2018). And are currently responsible for 30% of all deaths worldwide with most of the burden now occurring in developing countries (Young and Speight, 2020). This risk is increased for people with diabetes whose bodies cannot produce enough insulin or use insulin effectively. The aim of this study is to use cardiac biomarkers for stratification and assist with timely diagnosis of patients, as these indicators are released into the bloodstream due to stress or heart damage. Diabetes biomarkers: show a significant increase when comparing patients, who have MI with DM (in both genders) to the control group in each life stage. Cardiac biomarkers: show significant differences when, comparing patients having MI with DM to the control group in all life stages for (male & female), except (LDH in males in age (56-75) year. The same behavior was shown in patients having MI without DM, except (AST, LDH, CK-MB in age 56-75 & myoglobin in age 67-75) in females and (AST, LDH in age 56-75) in males. Vitamin D & Mg: shows significant difference when comparing patients having MI with DM to the control group in all life stages for (male & female). Urea & creatinine: show a significant difference when comparing (MI) patients with DM to the control group in life stages (56-66 in males and 56-75 in females). In conclusion, the study revealed significant differences in different biomarkers between myocardial infarction patients with and without diabetes compared to the control group.