Abstract

Physiological insulin concentrations modulate the allosteric properties of membrane-bound enzymes, such as rat erythrocyte acetylcholinesterase (AchE) and Na+/K+ ATPase (1). Modifications in both AchE and Na+/K+-ATPase enzymatic activities have been observed in human erythrocyte membranes obtained from patients affected by Insulin- dependent-Diabetes Mellitus (IDDM) (2,3).

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