Abstract
Diabetes mellitus is a chronic disease with serious health consequences. Diabetics are associated with depression of natural defence against infection, increases the risk of periodontal and periradicular diseases. However the effect of diabetes on periradicular tissues which differs structurally than periodontal tissuees are not discussed much. In this review, diabetes mellitus and its effect on pulp and periradicular tissues and its effect on treatment outcome are discussed. Some other studies suggests that some bacterial species are more prevalent in diabetics than non diabetics patients .Here diabetics is considered as a potential modulating factor for endodontic pathosis and alterations in the treatment pattern needed for the same are discussed.
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