Diabetes Mellitus among Adult Tuberculosis Patients Attending Tuberculosis Clinics in Eastern Ethiopia.

Lucy Tenaye,Ermiyas Mulu,Bizatu Mengiste,Negga Baraki

doi:10.1155/2019/7640836

Lucy Tenaye, Ermiyas Mulu + Show 2 more

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https://doi.org/10.1155/2019/7640836

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Abstract

Background Developing countries are suffering from the previously existing infectious diseases and alarmingly growing burden of noncommunicable diseases like diabetes mellitus. There is increased speculation that diabetes mellitus might attribute to high infectious diseases burden, such as tuberculosis. The global importance of diabetes mellitus as a tuberculosis-risk factor is still not a well-established fact. Thus, we conducted this study to determine the prevalence of diabetes mellitus and its associated factors among adult tuberculosis patients attending tuberculosis clinics. Methodology We conducted a cross-sectional survey, from March 10 to April 15, 2017, among 421 tuberculosis patients receiving tuberculosis treatment in health facilities of Dire Dawa City Administration Council, Eastern Ethiopia. Study participants were selected using systematic random technique, and data were collected using a structured questionnaire. Fasting blood sugar and anthropometric measurements were carried out for all participants. A logistic regression analysis was performed to identify factors associated with diabetes mellitus. Result The prevalence of diabetes mellitus in this study was 13.5%. Age 26–40 (AOR = 6, 95% CI: (1.28, 27.5)), age ≥41(AOR = 9, 95% CI: (1.9, 44.4)), and family history of diabetes (AOR = 3.14, 95% CI: (1.23, 8.02)) were found to have a significant association with diabetes mellitus. Conclusion This study found that the magnitude of diabetes mellitus among tuberculosis patients was higher than the national estimated prevalence of diabetes mellitus in Ethiopia. This study suggests the need for screening each tuberculosis patient for diabetes.

Highlights

Developing countries are suffering from the previously existing infectious diseases and alarmingly growing burden of noncommunicable diseases like diabetes mellitus. ere is increased speculation that diabetes mellitus might attribute to high infectious diseases burden, such as tuberculosis. e global importance of diabetes mellitus as a tuberculosis-risk factor is still not a well-established fact. us, we conducted this study to determine the prevalence of diabetes mellitus and its associated factors among adult tuberculosis patients attending tuberculosis clinics
Diabetic patients have the evidence of impaired cellmediated immunity, micronutrient deficiency, pulmonary microangiopathy, and renal insufficiency, all of which predispose to pulmonary tuberculosis (PTB) [3, 4]. e stress of a severe chronic infection may enhance existing insulin resistance and unmask an underlying β-cell deficiency leading to hyperglycemia; it is possible that the risk of diabetes mellitus (DM) is increased among people with TB, especially in the presence of other predisposing factors [5]
The problem of diabetes in TB patients of Ethiopia is not well documented; there are pocket studies conducted in a localized area, these pocket studies indicated that problem of diabetes among TB patients is increasing. erefore, this study aims to assess the diabetes mellitus comorbidity among patients on tuberculosis treatment

Summary

Introduction

Developing countries are suffering from the previously existing infectious diseases and alarmingly growing burden of noncommunicable diseases like diabetes mellitus. ere is increased speculation that diabetes mellitus might attribute to high infectious diseases burden, such as tuberculosis. e global importance of diabetes mellitus as a tuberculosis-risk factor is still not a well-established fact. us, we conducted this study to determine the prevalence of diabetes mellitus and its associated factors among adult tuberculosis patients attending tuberculosis clinics. Developing countries are suffering from the previously existing infectious diseases and alarmingly growing burden of noncommunicable diseases like diabetes mellitus. Ere is increased speculation that diabetes mellitus might attribute to high infectious diseases burden, such as tuberculosis. E global importance of diabetes mellitus as a tuberculosis-risk factor is still not a well-established fact. Us, we conducted this study to determine the prevalence of diabetes mellitus and its associated factors among adult tuberculosis patients attending tuberculosis clinics. Is study found that the magnitude of diabetes mellitus among tuberculosis patients was higher than the national estimated prevalence of diabetes mellitus in Ethiopia. Increases in the burden of noncommunicable diseases and aging populations are changing the importance of different risk factors for tuberculosis and the profile of comorbidities and clinical challenges for people with tuberculosis [6]. The early diagnosis of diseases is less common in developing countries. e originally existing disease masks the symptoms of the complicating disease. e prognosis and clinical course of each of the two conditions adversely affect the other [7]

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