Diabetes Insipidus and Pregnancy: A Case Report from Casablanca University Hospital (IBN ROCHD Maternity Hospital)

Abstract

Diabetes insipidus (DI) is a rare condition that complicates around two to three pregnancies out of 100,000 [1]. It is generally revealed by a polyuro-polydipsic syndrome or by serious hydro-electrolytic decompensations, mainly with neurological symptoms. The aetiologies of diabetes insipidus during pregnancy are either specific to pregnancy or gestational diabetes insipidus, or discovered before pregnancy. Gestational DI can occur in the absence of any obstetric pathology, in which case its pathophysiology can be explained by interactions between the placenta and ADH metabolism. Although there is no clear evidence of a direct link between gestational diabetes and pre-eclampsia, the frequent association observed between these two conditions may be explained by their occurrence in a high-risk environment. However, the polyuro-polydipsic syndrome is a symptom that is often trivialised by patients and may be reported spontaneously, so its frequent association with serious obstetric pathologies justifies its systematic investigation by questioning.