Abstract

Obesity and type II diabetes belong to the most serious public health challenges of the 21st century. Initially both diseases were typical of affluent societies. Currently both conditions however are increasingly found in low and middle income countries. In future obesity and diabetes are expected to reach epidemic proportions and affect developing countries to a greater extent than developed ones. A globalization of obesity and diabetes is observable. Recently prevalence rates increased, especially in Asia, the Near and Middle East, the Western Pacific region and even in Sub-Saharan Africa. Evolutionary Anthropology tries to understand the evolutionary mechanisms promoting rising obesity and diabetes type II rates. Homo sapiens evolved in an environment quite different from our recent one. Profound changes in physical activity patterns and nutritional habits during the last 10,000 years and increasingly during the last 200 years increased the risk of obesity and diabetes type II. Consequently our recent environment is called “obesogenic”. This mismatch has been recently observable among societies experiencing rapid cultural changes characterized by Westernization and modernization. This review focuses on obesity and type II diabetes from the viewpoint of evolutionary anthropology.

Highlights

  • The prevalence of obesity and type II diabetes has increased dramatically since the beginning of the 21st century and both are seen as global epidemics [1,2,3,4]

  • This review focuses on obesity and type II diabetes from the viewpoint of evolutionary anthropology

  • The environment experienced by members of the genus Homo and by Homo sapiens has been called the environment of evolutionary adaptedness (EEA) [85]

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Summary

Introduction

The prevalence of obesity and type II diabetes has increased dramatically since the beginning of the 21st century and both are seen as global epidemics [1,2,3,4]. More than 1.9 billion adults, 18 years and older, are overweight Of these over 600 million correspond to the definition of obesity [6]. From the viewpoint of public health the high rates of obesity among children as well as adults are a major concern. Can the worldwide epidemic of obesity and type II diabetes be interpreted as a result of a mismatch between the environmental conditions in which Homo sapiens has evolved and the recent environment? The aim of the present review is to discuss the rising rates of obesity and type II diabetes from the viewpoint of evolutionary anthropology Can the worldwide epidemic of obesity and type II diabetes be interpreted as a result of a mismatch between the environmental conditions in which Homo sapiens has evolved and the recent environment? The aim of the present review is to discuss the rising rates of obesity and type II diabetes from the viewpoint of evolutionary anthropology

Definition of Obesity
Definition of Diabetes Type II
Adverse Consequences of Obesity and Diabetes Type II
Prevalence of Obesity and Type II Diabetes
Obesity and Type II Diabetes from the Viewpoint of Evolutionary Anthropology
Obesity and Type II Diabetes in History
The Thrifty Genotype Hypothesis
Thrifty Phenotype Hypothesis
10. Evolutionary Medicine
12. The Neolithic Transition
13. Recent Obesogenic Environment
14. The Globalization of Obesity and Type II Diabetes
Findings
15. Conclusion
Full Text
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