Abstract

BackgroundDiabetes and hypertension disparities are pronounced among South Asians. There is regional variation in the prevalence of diabetes and hypertension in the US, but it is unknown whether there is variation among South Asians living in the US. The objective of this study was to compare the burden of diabetes and hypertension between South Asian patients receiving care in the health systems of two US cities.MethodsCross-sectional analyses were performed using electronic health records (EHR) for 90,137 South Asians receiving care at New York University Langone in New York City (NYC) and 28,868 South Asians receiving care at Emory University (Atlanta). Diabetes was defined as having 2 + encounters with a diagnosis of diabetes, having a diabetes medication prescribed (excluding Acarbose/Metformin), or having 2 + abnormal A1C levels (≥ 6.5%) and 1 + encounter with a diagnosis of diabetes. Hypertension was defined as having 3 + BP readings of systolic BP ≥ 130 mmHg or diastolic BP ≥ 80 mmHg, 2 + encounters with a diagnosis of hypertension, or having an anti-hypertensive medication prescribed.ResultsAmong South Asian patients at these two large, private health systems, age-adjusted diabetes burden was 10.7% in NYC compared to 6.7% in Atlanta. Age-adjusted hypertension burden was 20.9% in NYC compared to 24.7% in Atlanta. In Atlanta, 75.6% of those with diabetes had comorbid hypertension compared to 46.2% in NYC.ConclusionsThese findings suggest differences by region and sex in diabetes and hypertension risk. Additionally, these results call for better characterization of race/ethnicity in EHRs to identify ethnic subgroup variation, as well as intervention studies to reduce lifestyle exposures that underlie the elevated risk for type 2 diabetes and hypertension development in South Asians.

Highlights

  • Diabetes and hypertension disparities are pronounced among South Asians

  • In Atlanta, 75.6% of those with diabetes had comorbid hypertension compared to 46.2% in New York City (NYC)

  • Disaggregated data by race/ethnicity on disease prevalence are not available for all states; for example, diabetes prevalence among Asians is unavailable for Georgia [38]

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Summary

Introduction

Diabetes and hypertension disparities are pronounced among South Asians. There is regional variation in the prevalence of diabetes and hypertension in the US, but it is unknown whether there is variation among South Asians living in the US. Beasley et al Diabetology & Metabolic Syndrome (2021) 13:146 The purpose of this cross-sectional analysis is to compare diabetes and hypertension burden among South Asians receiving care at two large academic medical centers in New York City (NYC) and Atlanta. Understanding disparities across these populations may help disentangle issues related to environmental factors, health services, and/or immigration by region. These data will provide the foundation for discussion regarding similarities and differences between the populations across sites to inform the development of intervention strategies to reduce the burden of diabetes complications among South Asians in the US. Given the rapid growth of South Asians in these regions and their high burden of diabetes and hypertension, a critical need exists to tailor, translate, and disseminate evidence-based interventions to maximize impact in ameliorating co-morbid cardiovascular disease disparities [6]

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