Abstract
The global pandemic Coronavirus Disease 2019 (COVID-19) due to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is reported to be potentially severe in patients with morbid conditions. One common reported comorbidities is diabetes. We aimed in this study to precise the clinical characteristics and outcomes in a series of congolese diabetic patients affected by COVID-19 infection. We retrospectely studied from 256 COVID-19 patients, a cohort of 30 persons with previously known diabetes. The glycaemia controls have been obtained by plasma glucose assay. All patients have been tested positive to SARS-CoV-2 by RT-PCR method. The COVID-19 diabetic patients represented 11,7% of all COVID-19 patients with confidence interval of 95% [7,77-15,65]. Older individuals and male sex were predominent. Dyspnea and sauration of oxygen < 90 were significatives and added risk factors were noted in 63.3% of patients, particulary hyperglycaemia with hypertension or obesity. The mortality rate at the percentage of 36.7% was more prevalent in patients with added comorbidities (30%) versus without comorbidities (6.7%). Congolese COVID-19 diabetic patients of male sex and older age exhibiting arterial hypertension and obesity are the most exposed to severe COVID-19 and increasead mortality rate.
Highlights
In December 2019, cases of Coronavirus Disease 2019 (COVID-19) in the form of pneumonia due to the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) was first identified in Wuhan, Hubei Province, China1, 2
We aimed in this study to precise the clinical characteristics and outcomes in a series of congolese diabetic patients affected by COVID-19 infection
Patients and methods: We retrospectely studied from 256 COVID-19 patients, a cohort of 30 persons with previously known diabetes
Summary
In December 2019, cases of Coronavirus Disease 2019 (COVID-19) in the form of pneumonia due to the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) was first identified in Wuhan, Hubei Province, China . On March 11, 2020, Word Health Organization (WHO) declared COVID-19 a global pandemic. In Congo Brazzaville, the first case was declared on March 14, 2020. At the date of August 30, 2020, our database showed 4628 patients with laboratory confirmed COVID-19 of which 81 deaths were reported (SitRep 90, Congo). When SARS-CoV-2 infection occurs in people with pre-existing diabetes (type 1 and 2), there is a great risk of severe COVID-193, 5, 6. The present study aimed to access to the clinical characteristics and outcomes of a series of congolese diabetic patients with COVID-19 infection
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