Diabetes and COVID-19 in a Moroccan Hospital

Abstract

SARS-CoV-2 infection named COVID-19 is an infectious disease that emerged in December 2019 in Wuhan, Hubei Province, China. The infection has spread rapidly internationally and has had devastating consequences by producing large numbers of infected people and deaths as well as a negative socioeconomic impact. As for diabetes, it is a chronic, insidious, multi-factorial disease. In Morocco it is a major public health problem. This pandemic has raised questions about the risk of chronic diseases. Among them, diabetes; one of the most frequently reported comorbidities in patients with COVID-19. Our work consisted of a retrospective descriptive and analytical study of 72 cases of COVID- 19 associating Diabetes and COVID-19, collected at the Military Hospital Avicenne of Marrakech, during a period of 4 months between June 2021 and September 2021. The aim of this work was to define the clinical, paraclinical, therapeutic and evolutionary profile of the association between diabetes and COVID19, to identify the risk factors associated with the death of these patients through an analytical study and to propose recommendations for the management of diabetic patients with COVID-19. Hypertension was the most frequent comorbidity 44.4% followed by heart disease in 18.1%. The average age of our patients was 67 ±10 years with a male predominance (62.5%). The majority of our patients were vaccinated (70.8%). The presence of fever, as a clinical sign of Covid19 infection, was observed in the majority of patients (56 patients or 77.8%) followed by dyspnea in 56 patients or 77.8%. RT-PCR was positive in 68.1%, CRP was increased in 97.6%. Ferritinemia was increased in 83.3%. Blood glucose was increased in 89.7%. The extension of the lesions on thoracic CT of 25-50% was predominant in 48.4% of cases. In our study, the parameters of evolution, whose statistical variation was significantly associated with an unfavorable evolution were age>60 years, presence of digestive signs, ...