Abstract
An informed consent article using Hammond FM, Alexander DN, Cutler AJ, et al. PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury. BMC Neurology. 2016;16:89. https://doi.org/10.1186/s12883-016-0609-0 for a patient with pseudobulbar affect following stroke.
Highlights
Follow this and additional works at: https://digitalcommons.wayne.edu/crp Part of the Behavioral Medicine Commons, Family Medicine Commons, Medical Neurobiology
Informed Consent: Dextromethorphanquinidine is helpful for pseudobulbar affect disorder in stroke patients
This Informed Consent is brought to you for free and open access by the Open Access Journals at DigitalCommons@WayneState. It has been accepted for inclusion in Clinical Research in Practice: The Journal of Team Hippocrates by an authorized editor of DigitalCommons@WayneState
Summary
Mr Webb had two prior strokes, but through support from his wife, and mother, together with his sister, Ms Harris said he was able to regain almost full function without neurological deficit He was nearly nonverbal, limited to 1-2 word phrases and head gestures, with weakness in all four limbs. A wave of relief passed over his face as he completed the CNS-LS scale; the questions seemed to “read his mind.” He fervently pointed at his scores in response to the questions, at one point grabbing the paper from the clinician to emphasize his symptoms were occurring “Most of the time.”. During our initial purview of the clinical research literature, dextromethorphan-quinidine was suggested as a treatment for PBA During this acute hospitalization, we needed to decide if this therapy was appropriate for our patient with a condition most of us had never seen
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