Abstract
Dentistry is a continuously evolving science. Pathogenic oral biofilms are universal and chronic which leads to the destruction of the tissues due to the presence of the micro-organisms in its matrix. Treatment of bio-film-associated infections requires the development of new therapeutic strategies. In recent years, new nano-technology-based antimicrobials have been designed. Nanoparticle-mediated eradication uses the activation of the catalytic iron oxide nanoparticles (CAT-NP) coated with dextran (Dex-NZM). It results in the disruption of the biofilm by killing planktonic, antibiotic-resistant bacteria. It causes synergistic, antibiofilm efficacy which lowers the potential for bacterial resistance by free radical production, degradation of bacterial components, and causing bacterial cell death. Hence, the present study enumerates an alternative newer approach to the complete eradication and further prevention of oral biofilms.
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