Abstract

Osteoporosis, a public health problem is able to occur severe fractures and its prevalence increases in developing countries. Several factors involved in its pathogenesis. These factors are: Heredity, elderly, race, ethnicity, hormones, physical inactivity, sunlight exposure, vitamin D deficiency and certain drugs. In Africa, few data are available and the disease prevalence is maybe underestimated. In Senegal, measure of bone mineral density is recent. In this study, our objective was to determine DEXA patients profile and epidemiological, clinical characteristics of patients for densitometry examination. Thus, 43 cases were collected; lumbar and femoral sites were evaluated. Median lumbar T-score was 0.91 and the femoral T-score was 0.16. Osteopenia was found in 35% of patients and osteoporosis in 26%. Bone Mineral Density was abnormal in 60% of cases. This study is another proof of documented reality of osteoporosis in Senegal. It determines frequency in a population at risk. For the future, it opens way for further larger studies to get better profile of the patients and prevalence osteoporosis in Senegal.

Highlights

  • Osteoporosis was defined in 1993 as a “disease characterized by low bone mass and micro architectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk”

  • Osteopenia was found in 35% of patients and osteoporosis in 26%

  • Bone strength is estimated by non-invasive assessment of bone mineral density (BMD) by dual-energy X-ray absorptiometry (DXA)

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Summary

Introduction

Osteoporosis was defined in 1993 as a “disease characterized by low bone mass and micro architectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk”. As endorsed by the World Health Organization (WHO), the clinical diagnosis of osteoporosis is based on BMD measurements and the presence of fractures. Osteoporosis is the most common systemic bone disease osteopathy [1]. It is responsible for multiple fractures and can be severe. Many developing countries have a lower life expectancy These elements are likely to estimate the prevalence of osteoporosis as relatively low in the continent [3] [5]. These regional differences deserve to be further clarified and better explained.

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