Abstract
This paper reports the development of an express method for assessing the quality of biologically active substances derived from colostrum. We tested the hypothesis that there may be a dependence between the amount of protein that is part of the colostrum and its characteristic (a difference in molecular masses) and electrical conductivity.
 It has been shown that the colostrum contains several hundred proteins: it depends on the individual characteristics of cattle. The removal of lipids was accompanied by an increase in electrical conductivity from 5 % to 18 % compared to the whole colostrum while the subsequent removal of high-molecular proteins increased the electrical conductivity by 50‒100 % compared to skimmed colostrum: this depends on the individual characteristics of cattle. Such an individual feature of the colostrum composition reflects the uniqueness of the individual animal's metabolism. A mathematical model has been built for the dependence of the content of charged molecules in the solution of proteins on the molecular mass of proteins, which explains the relationship between electrical conductivity and the molecular mass of proteins.
 It was shown that there is a direct correlation between the colostrum electroconductivity and the temperature in a measuring cell in the range of temperatures from 14 °C to 19 °C. The electrical conductivity of colostrum components increased by no more than 20 % during storage (at a temperature of 3‒4 °C) up to 18 days, which is associated with protein degradation The electrical conduction method could be used to assess the colostrum composition during storage.
 Technology for obtaining different colostrum components (skimmed fraction and a fraction of low-molecular components) has been devised, as well as a method for assessing the quality of products based on the characteristics of electrical conductivity.
 Electrical conductivity is a promising method for assessing the quality of products that are derived from colostrum, at different shelf life at different stages of production: raw materials, fat removal, obtaining a fraction with a predefined composition of proteins
Highlights
Colostrum is a natural complex, unique in composition and biological activity, which regulates the activity of the immune system
The removal of lipids was accompanied by an increase in electrical conductivity from 5 % to 18 % compared to the whole colostrum while the subsequent removal of high-molecular proteins increased the electrical conductivity by 50‒100 % compared to skimmed colostrum: this depends on the individual characteristics of cattle
There is a direct correlation between the temperature in a measuring cell and electrical conductivity in the temperature range from 14 to 19 °C °C, due to the increased mobility of charged ions and molecules
Summary
Colostrum is a natural complex, unique in composition and biological activity, which regulates the activity of the immune system. Along with the transfer factor, colostrum contains a large number of other low-molecular biologically active compounds that remain under-researched and could be of great interest to the pharmacy. In the processing of colostrum, researchers face a number of unresolved issues and, above all, the standardization of finished products, which makes it difficult to devise new technologies for processing products with complex composition. This issue’s essence is to obtain a substance represented not by one but by a large number of different components. These criteria could be met by such a biophysical indicator as the electrical conductivity of liquid biological samples, in particular, colostrum
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
