Abstract
An efficient procedure is presented for the introduction of a 6- N-(2-cholesteroloxycarboaminoethyl)-or 6- N-[2-(9-fluorenylmethoxycarboamino)ethyl]moieties into adenosine, which is compatible with solid phase incorporation into antisense oligodeoxyribonucleotides and has the further advantage of lack of diastereomer formation.
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