Developmental pattern of cysteine sulphinic acid transaminase activity in some areas of mice nervous system.

Abstract

Abstract Cysteine sulphinic acid (CSA), a key intermediate in the major pathway of taurine metabolism, is catabolised by cysteine sulphinic acid decarboxylase (CSA-D) to hypotaurine and by the cysteine sulphinic acid transaminase (CSA-T) to glutamate. To continue earlier studies about the latter enzyme, the CSA-T activity was measured in the developing olfactory bulb, cerebellum, whole brain and retina of C57/B16 and C3H/He inbred mice. Differences in the developmental pattern between these two strains of mice in the retinae and in the olfactory bulb were observed. The significance of the differences is discussed.