Abstract
The objective of this study was to determine if caries susceptibility of offspring could be altered by maternal magnesium deficiency. Magnesium deficiency was evident by reductions in the magnesium content of serum, tibia, milk, and muscle as well as by an increase in both serum and kidney calcium. Maternal magnesium deficiency however was not severe enough to influence gestational weight gain, litter size, pup survival or weanling pup weight. Offspring originating from these magnesium deficient dams had less calcium, phosphorus and zinc in molar dentin compared to controls at the end of a 45-day caries test period. This apparent preeruptive reduction in mineral content of offspring dentin was associated with higher caries scores on the first and second molar buccal surface.
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