Developmental changes in motility and sensory gating: Strain differences

Abstract

sex--adjusted relative risk for new onset of major depression during the follow-up peri~xt in persons with history of insomnia at baseline was 4.0 (94% CI 2.2-7.0) and in persons with hypersomnia, 2.9 (95% C1 1.5-5.6). When history of other depressive symptoms (e.g., psychomotor retardation or agitation, suicidal ideation) was controlled, insomnia (but not hypersomnia) remained a significant risk factor for subsequent major depression. Complaints of 2 weeks or more of insomnia nearly every day might be a useful marker of subsequent onset of major depression.