Abstract
Objectives: A variety of developmental brain anomalies have been reported in individuals with myelomeningocele, Chiari malformation and hydrocephalus. While some authors have proposed that these anomalies are part of a spectrum that includes myelomeningocele and hydrocephalus, we addressed the alternative hypothesis that many of the brain anomalies seen with myelomeningocele are developmental disruptions secondary to early intrauterine hydrocephalus (IUH).
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