Developmental Aspects of Lycopene Action to Disaccharidases Kinetic Parameters of Chicken Jejunal Brush Border

Abstract

Lycopene is known as carotenoid with antioxidant properties associated with gap‐junction formation, prevents apoptosis, atherosclerosis and cancer. This study was undertaken to determine lycopene action to nutrition processes, particularly to ontogenetic kinetic parameters of main disaccharidases of chicken jejunal brush border (BB). Lycopene consumption provide Vmax increasing of sucrase and maltase of chicken jejunal BB from 2nd to 4th week and less significant decreasing of Vmax to 6th week of age. Maximal values of sucrase and maltase Vmax during ontogenesis were stated in 2–3‐weks of chicken in control (127.3 and 12.7 nmol/mg protein per sec) and experimental (154.3 and 17.2 nmol/mg protein per sec) groups respectively. Minimal values of sucrase and maltase Vmax were stated in 6‐weeks of chicken in control (56.4 and 11.3 nmol/mg protein per sec) and experimental (60.1 and 13.2 nmol/mg protein per sec) groups, respectively. Also it is shown significant Km decreasing from 2nd to 6th week of chicken in control and experimental groups for maltase and sucrase, respectively. Maltase and sucrase Ki of control chicken decreased from 75 to 57 mM and from 94 to 59 mM respectively. Maltase and sucrase Ki of experimental chicken decreased from 88 to 57 mM and from 93 to 66 mM respectively. Based on the received data it is concluded that lycopene affects nutrition processes in ontogenetic fashion in chicken jejunal brush border (BB).