Abstract

The development of the fertilizing capacity of mammalian epididymal spermatozoa has been studied mainly in rabbits (see Nishikawa & Waide, 1952; Bedford, 1966; Fulka & Koefoed-Johnsen, 1966; Orgebin-Crist, 1967) and occasionally in rats (Blandau & Rumery, 1964) and hamsters (Horan & Bedford, 1972). Although the results of these studies were not absolutely identical, even in the same species, it is generally agreed that the most proximal site from which fertile spermatozoa can be isolated is the corpus epididymidis and, in exceptional cases, the distal parts of the caput (Blandau & Rumery, 1964; Orgebin-Crist, 1967; Paufler & Foote, 1968). This paper describes the results of a study of the penetration activity of mouse epididymal spermatozoa. As distinct from preceding studies, in which the fertilizing capacity of spermatozoa was tested only in vivo, we

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