Development of the Formulation and Evaluation of the Anti-arthritic Activity of Vitex negundo Gel and Latex

Abstract

The important oil is Vitex negundo Linn. It is used in the treatment of eye diseases, toothache, infl ammation, leukoplakia, splenomegaly, skin ulcers, catarrh, rheumatoid arthritis, gonorrhea and bronchitis. It is also used as a tonic, insect repellent, galactagogue, menstrual agent, antibacterial, antipyretic and antihistamine. The plant component arrangements of V. negundo, are used commercially in a variety of Ayurvedic medicines and ointments for the treatment of a variety of ailments including rheumatism, arthritis, gout, cervical spondylitis, infl ammatory musculoskeletal, hemorrhoids (hemorrhoids), painful wounds, painful wounds. wounds, painful sores, burns and fungal infections of the skin. From the in vitro diff usion of drugs, we concluded that Emulgel composed of HPMC polymers can control drug secretion for a long time, which helps to prevent more fl uctuation and also reduces the cost of treatment. Due to the advantages of latex for improved spreadability, adhesion, viscosity, and extrudability, this new type of drug delivery is gaining popularity, besides systemic action, the local topical utility of hydrophobic dispensers is also of interest.