Abstract
A commercially viable composition for tablets containing dry meadowsweet [Filipendula ulmaria (L.) Maxim.] extract was developed. A direct pressing method was proposed and product quality standards were defined based on a study of the processing properties of the dry plant extract and tableting mixtures. A combined method for both qualitative (TLC on silica gel, UV spectroscopy) and quantitative (differential spectrophotometry using quercetin State Standard Sample) was developed for determination of flavonoids in the tablets. Three batches of tablets satisfying all requirements of the State Pharmacopoeia XIth Ed. and Industry Standard 64.7.170 – 75 were manufactured based on the dry meadowsweet extract.
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