Development of Stable Injectable Formulation by Freeze Drying Technique

Abstract

Drug stability is a significant problem that affects drug quality. Freeze drying is one of the techniques that can be used to develop stable drugs. This paper presents a new technique for developing regular drugs by a freeze-drying process with the potential for various applications in and the pharmaceutical industry. This review aims to improve the current systems from unstable to stable by freeze drying technique. systems are dangerous, which leads to the degradation of the drug. The freeze-drying process can be used for sound systems. Characteristics of proteins and peptides are the primary concern of the pharmaceutical industry. Freeze drying provides a new, safe, and effective way to preserve these substances without refrigeration or freezing. In the pharmaceutical industry, many efforts have been made to improve current protein formulations for injection. A new technique called freeze drying is emerging as a potential solution. This paper will explore the characteristics of freeze-drying and its possibilities for developing stable drugs in more detail. Especially complex protein-based drugs present significant challenges to manufacturers because their stability is low, and they often have harsh conditions that need to be stored such as being kept frozen or cooled on ice at all times.