Abstract
In the present work, spectrophotometric method was developed for analysis of mercaptopurine and dimercaprol to be applied in quality control and monitoring water pollution. These drugs are used for the treatment of cancer and heavy metal poisoning respectively. Both mercaptopurine and dimercaprol react with colourless anhydrous manganese (II) acetate in DMSO to form soluble brown coloured complexes which showed λmax at 350 nm and 360nm during spectrophotometric analysis. This newly developed method was successfully applied for analysis of commercial drugs and spiked water. The recovery of these drugs from commercial formulations and spiked water samples was in the range between 98.0-99.7% with RSDs in the range 0.56-1.50% that indicated high degree of accuracy and precision of the method.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
