Abstract
To detect 2,4,6-trinitrotoluene (TNT) using a displacement method over a surface plasmon resonance immunosensor, we developed sensor surfaces modified with a poly-(N-vinylformamideco-vinylamine), which was synthesized from a monomer, N-vinylformamide, and was hydrolyzed to produce amine groups, and TNT analogs. Poly-(N-vinylformamide-co-vinylamine) that reacted with succinic acid was used as a matrix of a sensor surface for increasing the number of antibody binding sites. 2,4-Dinitrophenyl glycine, 3-nitrophenyl acetic acid, and 4-nitrophenyl acetic acid were immobilized on the polymer-modified sensor surfaces. We evaluated the suppression ability of the sensor surface for nonspecific adsorption and determined the limit of detection (LOD) for TNT. As a result, a sensor chip suppressed nonspecific adsorption for 1 mg/mL bovine serum albumin and lysozyme. TNT was measured by the displacement method, and the LOD achieved over a 3-nitrophenyl acetic acid-modified sensor chip was 0.9 ng/mL (ppb).
Highlights
Activity monitoring systems are paramount in giving care to individuals, especially to elderly people.[1]
The smart chair is composed of six pressure sensors, an analog-to-digital (A/D) converter (MCP 3008), Raspberry Pi, and a conventional office chair
We developed a smart chair that can detect and classify five common activities performed in a sedentary position
Summary
Activity monitoring systems are paramount in giving care to individuals, especially to elderly people.[1]. Building systems to recognize activities performed by humans can improve the health-care services and the conditions of individuals as they age.[2,3]. Camera surveillance systems are effective in keeping track of human activities, they do not offer privacy to individuals. Wearable devices can be used to monitor daily activities.[4,5] several companies provide wearable solutions to protect individual privacy. These devices usually work on rechargeable batteries, which need periodic recharging. This makes the wearable devices inconvenient for daily use
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