Abstract
Alzheimer's disease—subsequently as AD in the text—represents a chronic neurodegenerative disease discussed very often in the recent period. It involves the G30 diagnosis expressing exactly AD and also the F00 diagnosis epitomising dementia in AD. The Slovak Republic has a very various population in terms of the disparities of the population localisation. The analysis is executed on the basement of the standardised mortality rate. It is calculated for the individual districts of the Slovak Republic to get a detailed spatial view and for each year of the explored period from 1996 to 2015 to get a time development. It has a considerably rising tendency. Therefore, the regional disparities of the standardised mortality rate of AD are analysed from an angle of view of its similarity, by its measurement in a form of a Euclidean distance approach. The results of the analysis offer the heat maps as the distance matrices in a graphic form and the maps of the individual districts too. These outputs reveal a very heterogeneous structure of the standardised mortality rate. Another graphic outcome demonstrates a distribution of its values among the districts throughout the whole Slovak Republic for the whole observed period. The results offer a comparison among the districts of the Slovak Republic too. The highest values and also the lowest values are reached in the different districts for the both sexes. Even, one district reaches the opposite result for the individual sexes. The age structure of the deceased population on the G30 diagnosis is also executed and the extreme values from an angle of a view of the districts are picked up. There are evident high differentiations between the individual districts of the Slovak Republic. The conclusion section involves the several key points and the potential suggestions for further research.
Highlights
During the last decade the mortality rate of Alzheimer’s disease has grown
Let us have a look at the situation in the field of standardised mortality rate on the G30 diagnosis
It is displayed for the two highest levels of administrative division of the territory of the Slovak Republic, for the self-governing regions as well as for the individual districts
Summary
During the last decade the mortality rate of Alzheimer’s disease has grown. This disease represents a degenerative brain disease and the most common cause of dementia. The person suffering from dementia has problems with their memory, language, thinking, and other cognitive skills which are affected in a way which lowers this individual's ability to perform common everyday life activities. The recently published study of Alzheimer’s Association describes an impact of AD on public health, including incidence, prevalence, mortality rates, and health care costs as well as the impact on society and carers. Since the biomarkers could be important for both the diagnostic process and for the estimation of prevalence and incidence of the disease, it should be useful to do the investigation of their usage [1]
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