Abstract
In the present study, Antimicrobial PVC films containing different amounts of clove oil as a plasticizer were prepared using traditional casting method. The physical and mechanical properties of the plasticized PVC membranes e.g. surface wettability were investigated. The increase of clove oil content demonstrated an increase in surface hydrophilicity and elongation to break the film. The thermogravemetric analysis revealed a decrease of polymer thermal stability by increasing clove oil concentration. The antibacterial activities against four different bacterial strains (two-gram positive: Staphylococcus aureus and Bacillus cereus & two-gram negative: Pseudomonas aeruginosa and Escherichia coli were promoted by addition of clove oil. Although the natural source of clove oil, the bio-evaluation of plasticized membranes showed an increase in hemolysis percent (%) and thrombus weight. It can be concluded that the addition of clove to PVC need to further studies for applying in blood bags.
Highlights
Starting from the 17th century, transfers of blood from healthy volunteer to patients was established as a medical treatment for some diseases and during a surgical operation (Greening et al, 2010)
PVC membranes were improved by utilized clove oil as a plasticizer
Fig. 1: water uptake PVC membranes plasticized with different contents of clove oil
Summary
Starting from the 17th century, transfers of blood from healthy volunteer to patients was established as a medical treatment for some diseases and during a surgical operation (Greening et al, 2010). Several problems were associated with using these old fashion vessels related to sterilizations, breakability, and the presence of air bubbles surround valves and during a blood transfusion (Ramsey and Schmidt, 2009; Duran, 1939). All of these reasons driving scientists to develop a new generation of flexible bags based on polymeric materials. The best performance can be achieved when the material is made softer and more flexible For this purpose, an additive described as a plasticizer is used, and the resulting plasticized, or soft, PVC finds widespread applications. From 30–40 percent of blood bags use DEHP as plasticizer
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