Development of potentiometric sensors for determining the concentration of ethan-1,2-dicarboxylic and 2-hydroxybenzoic acids

Kateryna Matorina,Olena Podpletnia

doi:10.15587/1729-4061.2016.75385

Kateryna Matorina, Olena Podpletnia

Open Access

https://doi.org/10.15587/1729-4061.2016.75385

Copy DOI

Abstract

The study suggests developed potentiometric sensors for determining the concentration of succinic and salicylic acids through using ion associates of succinic acid with safranin T and salicylic acid with safranin T as an electrodeactive material of a plasticized film membrane. It is an important task of analytic practice to determine the contents of succinic and salicylic acids in samples with a complex matrix (the environment, foodstuffs, and pharmaceuticals). The research has revealed analytical electrode characteristics of the designed sensors: the dynamic range (4–7 and 3–8 pC); the electrode function slope of 31 and 49 mV/pC; the minimum detectable concentration of С min =9·10 9 mol/L and 8·10 8 mol/L; the optimum pH range of 5.5–8.0 in the sensors operation; the conditioning time of 24 hours; the response time of 1–2 min; the lifetime of 11 months, respectively, for succinic acid and salicylic acid. We have found the selectivity coefficients (K sel ) for the devised sensors by the method of individual solutions with respect to carboxylic acids (citrate (1.0·10 3 ), tartaric (1.0·10 1 ), oxalic (3.0·10 3 ), and acetic (2.0·10 3 )). The method of additives was used to find the succinic acid content in samples of kvass (s r =4.0 %), red wine (s r =5.0 %), walnut leaves (s r =5.8 %), whereas salicylic acid was studied in salicylic ointment (s r =4.6 %) and the solution of salicylic acid and resorcinol (s r =4.0 %). The correctness of the results was tested by the alternative alkalimetry method. The reproducibility of the suggested ionometric and alternative alkalimetric methods by the Fisher criterion (F exp <F tabl ) was found to be the same. The proposed sensors can be used in analytical laboratories for quality control of foodstuffs and pharmaceuticals.

Highlights

An important contemporary task is to analyse and control the quality of foodstuffs, agricultural raw materials, and pharmaceuticals
To assess the safety of products of food and pharmaceutical industries, it is necessary to control contaminants, food additives, identify fraud, and assess the quality of manufactured products [1,2,3,4]. These issues are traditionally addressed with analytical methods, including gas and high pressure liquid, ion exchange, thin-layer and size-exclusion chromatography, atomic absorption spectroscopy, inductively coupled plasma mass spectrometry, capillary electrophoresis, stripping voltammetry, conductometry, and ionometry
Pregnant women are not recommended to use products that contain it because of increased risk of Reye’s syndrome

Summary

Introduction

An important contemporary task is to analyse and control the quality of foodstuffs, agricultural raw materials, and pharmaceuticals. To assess the safety of products of food and pharmaceutical industries, it is necessary to control contaminants, food additives (preservatives, sweeteners, antioxidants, dyes, etc.), identify fraud, and assess the quality of manufactured products [1,2,3,4]. These issues are traditionally addressed with analytical methods, including gas and high pressure liquid, ion exchange, thin-layer and size-exclusion chromatography, atomic absorption spectroscopy, inductively coupled plasma mass spectrometry, capillary electrophoresis, stripping voltammetry, conductometry, and ionometry. The overdose symptoms are: headaches, tinnitus, hearing disorders and vision impairment, nausea, vomiting, abdominal pain, diarrhoea, excessive sweating, low blood pressure and bleeding, impaired consciousness, and cramps

Literature review and problem statement

The aim and tasks of the study

The research results on the synthesized succinate and salicylate sensors

Conclusions