Abstract
Approximately 150 medical cyclotrons are installed in Japan for the production of conventional positron emission tomography (PET) radionuclides for routine nuclear medicine practice. The PET Center of Tokyo Metropolitan Institute of Gerontology (TMIG) was the 19th PET Center to be established in Japan. It has provided continuous service since 1990, performing basic and clinical studies as well as clinical diagnosis, and underwent an upgrade in 2013. It is clear that the novel PET radiopharmaceuticals can provide new tools for research and exploration of the PET-based diagnosis of various diseases. From this standpoint, we have undertaken the development of novel PET radiopharmaceuticals specifically for the investigation of brain function. The status of the development of the novel PET radiopharmaceuticals for clinical use at TMIG 2010-2019 is reviewed here.
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