Abstract
This study proposes the development of a new photoelectrochemical (PEC) sensor for the determination of dopamine (DA) at nanomolar levels. The PEC sensor was based on a physical mixture of bismuth vanadate (BiVO4) with nanocomposite molecularly imprinted poly(acrylic acid) (MIP-AA) grafted onto MWCNTox by using the surface-controlled radical polymerization strategy with an INIFERTER reagent. XRD, diffuse reflectance spectroscopy (DRE), SEM, TEM, and TGA were employed to characterize the materials. Photoelectrochemical analyses were carried out with GCE/BiVO4/MIP-AA sensor under visible light using a potential of 0.6 V, phosphate buffer (0.1 mol L−1) at pH 7.0, and modifying the GCE with a film composed of monoclinic BiVO4 at 3.5 mg mL−1 and nanocomposite MIP prepared with acrylic acid (MIP-AA) at 0.1 mg mL−1. The proposed method using the GCE/BiVO4/MIP-AA sensor presented a limit of detection (LOD) of 2.9 nmol L−1, a linear range from 9.7 to 150 nmol L−1 and it was successfully applied for analysis of DA in urine samples using external calibration curve yielding recovery values of 90–105%. Additionally, the proposed PEC sensor allowed DA determination without interference from uric acid, ascorbic acid, epinephrine, norepinephrine, and other unwanted interferences.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.