Abstract

In this paper, a non-enzymatic amperometric glucose sensor working at very low applied potential of 0.2 V was developed based on a nano-TiO2 coated aluminum tip electrode. A highly fractured TiO2 film with porous structures was synthesized on aluminum substrate via dip coating method followed by annealing at 350 °C. Glucose sensing properties were determined via amperometric measurement and showed high sensitivity of 0.766 mA/mM-cm2 over a linear range of 0.55 to 55 mM with a lower detection limit of 0.55 mM of glucose. This indicates that the slack porous nano-TiO2 is an attractive material for use in the fabrication of biosensors, particularly non-enzymatic sensors, because of its direct electrochemistry, high specific surface area, and unique nanostructure for efficient immobilization of bio-molecules.

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