Abstract
Open AccessConference Report Development of Modified Release Pellets via Dry Powder Coating by M. SMIKALLA 1,* and N. A. URBANETZ 2 1 Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Duesseldorf, Germany 2 Research Center Pharmaceutical Engineering, Graz University of Technology, Graz, Austria * Author to whom correspondence should be addressed. Sci. Pharm. 2010, 78(3), 583; https://doi.org/10.3797/scipharm.cespt.8.LPPT03 Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010 Download PDF Citation Export BibTeX EndNote RIS Cite This Paper
Highlights
Dry powder coating is a relatively new technique to coat substrates without the use of any organic solvent or water
One critical parameter in dry powder coating is the coating efficiency which describes how much of the applied coating material adheres to the cores
Theophylline pellets were used as cores and ethylcellulose, hydroxypropylmethylcellulose acetate succinate (HPMCAS) or Eudragit RS® as coating polymer
Summary
Dry powder coating is a relatively new technique to coat substrates without the use of any organic solvent or water. 1 Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Duesseldorf, Germany 2 Research Center Pharmaceutical Engineering, Graz University of Technology, Graz, Austria The film forming polymer is applied as a powder to the cores to be coated leading to reduced process times [1]. Excipients like plasticizers, preferably in liquid form, are often needed to soften the polymer in order to get a functional film.
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