Abstract

Sweat contains numerous biomarkers, including glucose, which can provide valuable insights into an individual’s metabolic state. Noninvasive glucose monitoring eliminates the need for frequent finger pricks or blood samples, offering greater convenience and reducing discomfort for individuals with diabetes. These biosensors are designed to detect and quantify glucose levels through various sensing mechanisms, such as enzymatic reactions or electrochemical measurements. The integration of biosensors into wearable devices, such as smartwatches, patches, or flexible electronics, allows for mobile glucose monitoring in sweat. Accurate glucose measurements require calibration and validation against reference measurements, such as blood glucose levels. Research focuses on developing calibration algorithms and improving the accuracy and reliability of mobile glucose biosensors in sweat.

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