Development of Microdevices Combining Machine and Life Systems

Abstract

A number of recent studies have exploited the sizes and functional properties of microdevices and cellular mechanical components to construct bio-microdevices. As the scale of microdevices can accommodate different cell sizes and processing capabilities, a number of efficient bioreactors and bioassay systems using cellular functions have been produced. To date, the main focus of these devices has been the analysis of cellular chemical functions. On the other hand, our concept is to use cells as components of devices for fluidic control. To date, various devices have been developed that exploit cellular mechanical functions. The working principle of these devices is novel because they only use chemical energy inputs. In this letter, the recent progress of this study and its characteristics are reviewed.