Abstract
Purpose of study: Vibrating flow blood pump (VFP) is an original blood pump which is designed in Tohoku University. It consists of a vibrating tube and a valve. The purpose of this study is to develop an integrated oxygenator using VFP. The integrated oxygenator is expected to be applied as an extracorporeal membrane oxygenation or a percutaneous cardiopulmonary support system. Materials and Methods: The length of the vibrating tube is 100mm, and the diameter of the tube is 30mm. A jellyfish valve, which is also developed in our research group, is located at an end of the vibrating tube to produce an oscillated flow. The wounded hollow fibers as a mat are wrapped in the vibrating tube. The hollow fiber is made of polymethylpenten, the outer diameter is 380 micron. Results: The surface area of capillary membrane is 0.7 m2 and the priming volume of whole system is 75 ml. An electric motor actuates the vibrating tubes using a simple small crankshaft mechanism. The amplitude of the tube is 8 mm, and the frequency is about 10 Hz. The oxygen transfer rate is about 100 ml/min, when the blood flow is 2 L/min, and the V/Q ratio is 1:1.
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