Abstract
Introduction. Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. Case Presentation. Because of increasing epigastric and abdominal pain, abdominal ultrasound was performed in a 37-year-old male professional bodybuilder. A hyperechoic lesion in the liver was detected in segment VI. The magnetic resonance imaging showed hepatomegaly and confirmed the lesion, which showed features of a hepatocellular adenoma (HCA). Laboratory values were inconspicuous. After laparoscopic segmentectomy the histological examination revealed HCC. Conclusion. While the development of HCA in the liver by chronic intake of AAS is well known, little is known about the association with HCC. The presented case may indicate aetiological association of chronic intake of AAS and the development of HCC.
Highlights
Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC)
We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse
While the development of hepatocellular adenoma (HCA) in the liver by chronic intake of anabolic androgenic steroids (AASs) is well known, little is known about the association with HCC
Summary
Many different etiological factors are involved in the development of hepatocellular carcinoma (HCC). We report the case of HCC in a 37-year-old male professional bodybuilder with extensive anabolic androgenic (AAS) steroid abuse. While the development of HCA in the liver by chronic intake of AAS is well known, little is known about the association with HCC. The presented case may indicate aetiological association of chronic intake of AAS and the development of HCC. Many different aetiological factors are involved in the development of HCC. Long-term use of oral contraceptives and high-dose anabolic androgenic steroids (AASs) are described in the literature as further, but rare, aetiologic factors [1, 3]. We present a case of a previously healthy 37-year-old male professional bodybuilder with HCC probably based on extensive anabolic abuse
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