Development of empirical model and controller for negative pressure wound therapy system

Abstract

Negative pressure wound therapy process usually helps to heal the diabetic open wound much better by applying smooth vacuum process. This therapy gives the positive effects based on the stimulation of formation of granulation tissue, blood flow, angiogenesis, cell proliferation, accelerated secondary wound closure and removal of bacteria from the wound. Generally maintaining the negative pressure in the system is a challenging task which desires the patient to feel more relaxed during the period of healing. In this work attaining and authenticating of a mathematical model of a negative pressure wound therapy system is presented. The established model is based on the vacuum system along with the pump and other elements. The objective of the model is to perform with the design and analysis of a proportional integral derivative control algorithm. It has been validated that this algorithm, is suitable in controlling the vacuum pressure in the chamber, which is based on the simulation on MATLAB Simulink.