Development of effervescent tablet formulation for rapid control of mosquito problem in early stages from different breeding sites

Abstract

Mosquito problem remains a major problem due to unavailability of effective formulation for controlling mosquito at the starting stages. The aim of this study was to develop a neem based effervescent tablet for immediate and fast destruction of mosquito larvae in any unrecognized ecosystems like stagnant water after rain or water blockage or for household applications. Effervescent tablet was prepared by the 30% neem oil absorbed over silica and then combine acids/acid salts and bicarbonates in definite proportion (citric acid, tartaric acid, sodium bicarbonate and sodium carbonate). The powdered mixer was then compressed in tablet machine. The tablet shows bubbling reaction by releasing CO2 when dispersed in water. The tablet was evaluated for hardness, thickness, disintegration, weight variation, Ph, content % and accelerated storage test. The tablet shows all the physicochemical parameters within the limits. Bio-efficacy evaluation was tested against larvae. It shows 75–90% mortality for Aedes agyptii larvae.