Abstract
Dissolution testing is well established in pharmaceutical compendia as a means of assessing finished product quality. Oral extended-release products present unique challenges in the development of dissolution test methods for their characterization. Although the current focus in the field has been on the use of dissolution testing in the later stages of product development for the purpose of establishing in vivo/in vitro correlations, the creative use of dissolution techniques can speed the initial stages of formulation development, particularly in the case of extended-release products.
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