Abstract

This study aims to develop the dencichine plus Yunnan Baiyao band-aid, and test the hemostatic effect in traumatic incision of the new band-aid, the stability of dencichine was measured by HPLC beforehand. After that, several groups with different material were pasted on longitudinal incision of SD rats. Bleeding time and blood loss was determined, observing the healing of the wounds. The result was that the stability of dencichine by HPLC proved to be steady beforehand. Compared with blank control group, the other groups could shorten bleeding time (p<0.01), and reduce blood loss (p<0.01), whats important is that the Yunnan Baiyao band-aid groups were much better about the healing of the wounds than gauze groups. The results indicates that it is obvious that dencichine plus Yunnan Baiyao band-aid has a significant effect on longitudinal incision, and it helps the wound to heal. Dencichine plus Yunnan Baiyao band-aid has economic prospect in marketing appliance.

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