Abstract

Complex three-dimensional (3D) porous scaffolds with macro-pore size of 400–800 μm based on polyvinyl alcohol (PVA) powder were successfully developed by selective laser sintering (SLS) technology. The PVA scaffolds had customizable shape, controlled and totally interconnected porous structure, and high porosity. The microstructure and mechanical property were performed for their suitability for tissue engineering (TE). The results showed that PVA did not decompose while the degree of crystallization decreased in a given sintering condition. Moreover, there were micro-pores with sizes of 20–100 μm in the scaffold. The actual porosity of sintered scaffolds could be up to 82.35%, which was higher than the value of the designed models. An in vitro biocompatibility test showed MG-63 cells could well spread on the scaffold surface. The presented work demonstrates the favorable potential of PVA powder as TE scaffolds fabricated via SLS.

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