Abstract
Spirulina has widely been highlighted as a source of bioactive material that can be impregnated into dressing materials. The aim of this study was to widen the application fields of Spirulina extract-containing nanofiber, which has been suggested as an attractive dressing material in several previous studies. The bioactivity release pattern, water absorbance, and mechanical strength must be controllable. Spirulina extract was physically impregnated inside a nanofiber without significant chemical bonding to polycaprolactone or alginate polymers. This led to an initial burst and continual release of bioactive molecules from the nanofiber. By altering the concentration of Spirulina extract, mechanical strength and water absorbance were controllable. In addition, the dressing patch showed no cytotoxicity towards human epithelial cells, not causing skin-irritation. This indicates that the coaxially fabricated patch is a controllable dressing material that can be customized to have a specific mechanical strength, water absorbance, and bioactive release pattern, making it suitable for wide applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
