Development of Coagulopathy and Pancreatitis Due to Saw Palmetto Used for Urinary Symptoms

Abstract

Aim: Serenoa repens, commonly known as saw palmetto, is a widely used herbal supplement for lower urinary tract symptoms. However, data regarding the toxicity of this dietary supplement is limited. In this study, it is aimed to emphasize that herbal extracts such as saw palmetto can cause coagulation disorder and pancreatitis. Case Presentation: In this case report, we present a 60 year-old male patient using saw palmetto extract for urinary stone disease and urinary tract symptoms. The patient had widespread ecchymoses on the tip of the tongue, trunk and extremities. The coagulometric tests of the patient, who did not use any anticoagulant drugs, were prolonged; renal failure had also developed. Vitamin K and fresh frozen plasma were used to treat the coagulopathy. The patient, who also developed acute pancreatitis in the days following hospitalization, was discharged on the 15th day without any additional complications. Conclusion: Herbal supplements are widely used in medical practice. Saw palmetto extracts may have different adverse effects including abdominal pain, headache, hepatotoxicity, coagulopathy, and pancreatitis. Patients using these supplements should be aware of these effects of saw palmetto.