Abstract
The cholinergic differentiation of enteric ganglia in embryos of chick and quail was studied with particular reference to cholinesterase and choline acetyltransferase activities. Differentiation during normal development was compared with that obtained after culture of the neural primordium or neural crest in direct association with aneural hindgut. Biochemically differentiated cholinergic ganglia developed in explants containing cells from either the ‘vagal’ (presumptive cholinergic) or ‘truncal’ (presumptive adrenergic) levels of the neural crest. Neither extra-intestinal migration of neural crest cells nor the presence of central preganglionic fibres is a prerequisite for enteric ganglion differentiation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have