Development of biocompatible superelastic materials and shape memory implants based on titanium nickelide for the creation of highly effective medical technologies

Abstract

The paper presents fundamental and applied research in a new direction in science and technology, which has a world priority – medical materials and implants with shape memory. The main directions of the development of a new generation of more advanced biocompatible superelastic implantable materials and long-term shape memory implants based on titanium nickelide are formulated. The physical, biological principles of creating a new class of biocompatible superelastic materials based on titanium nickelide with a certain set of properties for various fields of medicine using technologies of induction melting, self-propagating high-temperature synthesis, and sintering are presented.Among the materials created, the development of alloys for long-term functioning in a living organism is of great importance: monolithic elastic, porous and ultra-thin porous-permeable materials, fabric and textile materials made of thin filaments based on titanium nickelide. The main medical and technical requirements for a new class of implants of the future have been identified. Criteria for the biomechanical compatibility of metallic materials under deformation conditions in aggressive tissue media have been determined. Conditions are formulated under which monolithic and porous materials exhibit properties that are optimal for implantation. A comprehensive study of the properties of cell incubators made of porous titanium nickelide was carried out, and the morphological characteristics and patterns of cell development in the porous structure of bulk biomaterials made of titanium nickelide were revealed.The main directions of creation of unique medical technologies based on the developed materials are characterized. The principles of application of biocompatible superelastic materials in various fields of medicine are described. Titanium nickelide-based materials and implants with shape memory implanted into the body are intended for a wide range of medical purposes in dentistry, traumatology, surgery, ophthalmology, vascular surgery, oncology and other fields of medicine as implants for osteosynthesis, endoprosthetics, replacement of tissue defects, creating anastomoses and support frames of organs.